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Supercritical Fluid Chromatography (SFC)
Product Information
Technique
Phenomenex offers Supercritical Fluid Chromatography (SFC) columns in Achiral and chiral mdoes. Explore advanced SFC solutions for fast separations using CO2.
In supercritical fluid chromatography (SFC) the mobile phase consists of carbon dioxide (CO2) above or near its critical state (temperature >31.1 °C and pressure >73.8 bar) in combination with an organic modifier such as methanol. This relatively non-polar mobile phase can be used with stationary phases typically used in normal or reversed phase HPLC, and the low viscosity and high diffusivity of supercritical CO2 relative to the solvents typically used in HPLC translates into much faster separations. Typically SFC columns can be used in two modes:
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